Many people suffer from severe depression that does not get better with normal medicine or therapy, even after trying for decades. To solve this, doctors tested a small device implanted under the skin of the chest that sends gentle electrical pulses to the vagus nerve. This treatment helped the "sickest" patients finally feel relief. After two years, most people who improved stayed better, and 1 in 5 became completely symptom-free, allowing them to finally return to a normal life.